Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Veterinary Clinics: Exotic Animal PracticeAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Pet Ownership 2012. American Veterinary Medical Association.(Available at:) (Accessed December 27, 2021)
- ACLAM position statement on pain and distress in research animals.J Am Assoc Lab Anim Sci. 2016; 55: 821
- Rodent analgesia.Vet Clin North Am Exot Anim Pract. 2011; 14: 81-92
- Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures.Lab Anim. 2009; 43: 232-238
- Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: Are we making progress?.Altern Lab Anim. 2005; 33: 119-127
- Reported analgesic and anaesthetic administration to rodents undergoing experimental surgical procedures.Lab Anim. 2009; 43: 149-154
- Clinical management of pain in rodents.Comp Med. 2019; 69: 468-489
- Sedation and anesthesia in rodents.Vet Clin North Am Exot Anim Pract. 2022; 25: 211-255
- Synergistic interaction between butorphanol and dexmedetomidine in antinociception.Eur J Pharm Sci. 2020; 149105322
- The Index of Legally Marketed Unapproved New Animal Drugs for Minor Species. 2009.(Available at:) (Accessed December 21, 2021)
- The modified WHO analgesic ladder: Is it appropriate for chronic non-cancer pain?.J Pain Res. 2020; 13: 411-417
- Multimodal approaches and tailored therapies for pain management: the trolley analgesic model.J Pain Res. 2019; 12: 711
- Local and regional anesthesia.Vet Clin Small Anim Pract. 2000; 30: 839-857
- Basic principles of anaesthesia.in: Flecknell P. Laboratory animal anaesthesia. 4th edition. Academic Press, San Francisco, CA2016: 1-75
- FDA. EMLA CREAM (lidocaine 2.5% and Prilocaine 2.5%). Updated November 2018.(Available at:) (Accessed March 2, 2022)
- Evaluation of EMLA cream for preventing pain during tattooing of rabbits: Changes in physiological, behavioural and facial expression responses.PLoS One. 2012; 7
- The use of eutectic mixture of lidocaine and prilocaine in mice (Mus musculus) for tail vein injections.Vet Anaesth Analg. 2014; 41: 654-659
- Effects of topical anesthetics on behavior, plasma corticosterone, and blood glucose levels after tail biopsy of C57BL/6NHSD mice (Mus musculus).J Am Assoc Lab Anim Sci. 2016; 55: 443-450
- An extended release local anaesthetic: Potential for future use in veterinary surgical patients?.Vet Med Sci. 2016; 2: 229-238
- Use of liposomal bupivacaine for postoperative analgesia in an incisional pain model in rats (Rattus norvegicus).J Am Assoc Lab Anim Sci. 2017; 56: 63-68
- Establishment of an animal model of epidural anesthesia and sedative tail-flick test for evaluating local anesthetic effects in rats.Exp Anim. 2013; 62: 137-144
- Epidural analgesia with a combination of bupivacaine and buprenorphine in rats.J Vet Med A Physiol Pathol Clin Med. 2001; 48: 303-312
- The clinical pharmacology of cyclooxygenase-2–selective and dual inhibitors.Vet Clin North Am Small Anim Pract. 2006; 36: 1061-1085
- The mechanisms of the inhibitory effects of nonsteroidal anti-inflammatory drugs on bone healing: A concise review.J Clin Pharmacol. 2003; 43: 807-815
- Comparison of the effects of oral or subcutaneous carprofen or ketoprofen in rats undergoing laparotomy.Vet Rec. 1999; 144: 65-67
- Analgesia of Small Mammals.Vet Clin North Am Exot Anim Pract. 2001; 4: 47-56
- Anesthesia, analgesia, and sedation of small mammals.in: Quesenberry K.E. Orcutt C.J. Mans C. Ferrets, rabbit, and rodents. 4th edition. WB Saunders, St. Louis, MO2021: 536-558
- Analgesia and post-operative care.in: Flecknell P. Laboratory animal anaesthesia. 4th edition. Academic Press, San Francisco, CA2016: 141-192
- Using the mouse grimace scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.J Am Assoc Lab Anim Sci. 2012; 51: 42-49
- Rodent analgesia: Assessment and therapeutics.Vet J. 2018; 232: 70-77
- Efficacy of common analgesics for postsurgical pain in rats.J Am Assoc Lab Anim Sci. 2015; 54: 420-425
- Effects of NSAIDs on bladder function in normal and cystitis rats: A comparison study of aspirin, indomethacin, and ketoprofen.J Pharmacol Sci. 2004; 95: 458-465
- Adverse effects of incorporating ketoprofen into established rodent studies.J Am Assoc Lab Anim Sci. 2008; 47: 20-24
- A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats.J Am Assoc Lab Anim Sci. 2012; 51: 832-841
- A comparison of the effects of buprenorphine, carprofen and flunixin following laparotomy in rats.J Vet Pharmacol Ther. 1994; 17: 284-290
- Evaluation of a short duration behaviour-based post-operative pain scoring system in rats.Eur J Pain. 2003; 7: 397-406
- Postoperative analgesia due to sustained- release buprenorphine, sustained-release meloxicam, and carprofen gel in a model of incisional pain in rats (Rattus norvegicus).J Am Assoc Lab Anim Sci. 2016; 55: 300-305
- Concentration-dependent toxicity after subcutaneous administration of meloxicam to C57BL/6N mice (Mus musculus).J Am Assoc Lab Anim Sci. 2018; 58: 802-809
- Injection-site reactions to sustained-release meloxicam in sprague dawley rats.J Am Assoc Lab Anim Sci. 2020; 59: 726-731
- Injection reactions after administration of sustained-release meloxicam to BALB/cJ, C57BL/6J, and Crl:CD1(ICR) mice.J Am Assoc Lab Anim Sci. 2021; 60: 176-183
- The analgesic effects of oral paracetamol in two strains of mice undergoing vasectomy.Animals. 2009; 43: 357-361
- Lidocaine and bupivacaine as part of multimodal pain management in a C57BL/6J laparotomy mouse model.Sci Rep. 2021; 11: 1-17
- Sustained-release and long-acting opioid formulations of interest in zoological medicine.in: Fowler’s Zoo Wild Anim Curr Ther. vol. 9. WB Saunders, St. Louis, MO2019: 151-163
- A practical approach for the management of the mixed opioid agonist-antagonist buprenorphine during acute pain and surgery.Mayo Clin Proc. 2020; 95: 1253-1267
- A narrative pharmacological review of buprenorphine: A unique opioid for the treatment of chronic pain.Pain Ther. 2020; 9: 41-54
- Opioid receptors signaling network.J Cell Commun Signal. 2021; (Epub ahead of print): 1-9https://doi.org/10.1007/s12079-021-00653-z
- Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: structural determinants and role in antinociception.J Pharmacol Exp Ther. 1995; 274: 1263-1270
- Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists.Biochem Pharmacol. 1998; 56: 553-559
- Analgesic activity of tramadol and buprenorphine after voluntary ingestion by rats (rattus norvegicus).J Am Assoc Lab Anim Sci. 2016; 55: 74-82
- Evaluation of buprenorphine in a postoperative pain model in rats.Comp Med. 2009; 59: 60-71
- Opioid-induced hyperalgesia in patients after surgery: A systematic review and a meta-analysis.Br J Anaesth. 2014; 112: 991-1004
- Opioid-induced hyperalgesia in a mice model of orthopaedic pain: Preventive effect of ketamine.Br J Anaesth. 2010; 104: 231-238
- Differential opioid tolerance and opioid-induced hyperalgesia: A clinical reality.Anesthesiology. 2016; 124: 483-488
- Buprenorphine-induced hyperalgesia in the rat.Eur J Pharmacol. 2011; 651: 89-95
- Molecular mechanisms of opioid tolerance: From opioid receptors to inflammatory mediators (Review).Exp Ther Med. 2021; 22: 1-8
- A preclinical comparison between different opioids: antinociceptive versus adverse effects.Pharmacol Biochem Behav. 2005; 80: 309-326
- Comparative actions of the opioid analgesics morphine, methadone and codeine in rat models of peripheral and central neuropathic pain.Pain. 2005; 116: 347-358
- Evaluation of self-injurious behavior, thermal sensitivity, food intake, fecal output, and pica after injection of three buprenorphine formulations in rats (Rattus norvegicus).Am J Vet Res. 2018; 79: 697-703
- Methylnaltrexone prevents morphine-induced kaolin intake in the rat.Life Sci. 2004; 74: 2685-2691
- Preclinical studies of opioids and opioid antagonists on gastrointestinal function.Neurogastroenterol Motil. 2004; 16: 46-53
- Butorphanol-mediated antinociception in mice: partial agonist effects and mu receptor involvement.J Pharmacol Exp Ther. 1997; 282: 1253-1261
- Evaluation of the paw withdrawal latency for the comparison between tramadol and butorphanol administered locally, in the plantar surface of rat, preliminary study.PLoS One. 2021; 16: e0254497
- Reduction of the sevoflurane minimum alveolar concentration induced by methadone, tramadol, butorphanol and morphine in rats.Lab Anim. 2012; 46: 200-206
- The magnitude and duration of the analgesic effect of morphine, butorphanol, and buprenorphine in rats and mice.Contemp Top Lab Anim Sci. 2000; 39: 8-13
- Pharmacokinetics of sustained-release analgesics in mice.J Am Assoc Lab Anim Sci. 2014; 53: 478-484
- Buprenorphine induces ceiling in respiratory depression but not in analgesia.Br J Anaesth. 2006; 96: 627-632
- Current knowledge of buprenorphine and its unique pharmacological profile.Pain Pract. 2010; 10: 428-450
- Effects of time and storage conditions on the chemical and microbiologic stability of diluted buprenorphine for injection.J Am Assoc Lab Anim Sci. 2017; 56: 457-461
- Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats.PLoS One. 2017; 12: e0176443
- Evaluation of volume of intramuscular injection into the caudal thigh muscles of female and male BALB/c mice (Mus musculus).J Am Assoc Lab Anim Sci. 2018; 57: 35-43
- Serum buprenorphine concentrations and behavioral activity in mice after a single subcutaneous injection of simbadol, buprenorphine SR-LAB, or standard buprenorphine.J Am Assoc Lab Anim Sci. 2021; 60: 661-666
- Antinociceptive effects of voluntarily ingested buprenorphine in the hot-plate test in laboratory rats.Lab Anim. 2017; 51: 264-272
- Use of oral buprenorphine ('buprenorphine jello’) for postoperative analgesia in rats - A clinical trial.Lab Anim. 1999; 33: 169-174
- Evaluation of self-injurious behavior, food intake, fecal output, and thermal withdrawal latencies after injection of a high-concentration buprenorphine formulation in rats (Rattus norvegicus).Am J Vet Res. 2018; 79: 154-162
- Adverse effects on growth rates in rats caused by buprenorphine administration.Lab Anim. 2000; 34: 202-206
- Association of nausea with buprenorphine analgesia for rats.Lab Anim. 2017; 46: 242-244
- Buprenorphine for pain relief in mice: repeated injections vs sustained-release depot formulation.Lab Anim. 2015; 49: 177-187
- Duration of action of sustained-release buprenorphine in 2 strains of mice.J Am Assoc Lab Anim Sci. 2012; 51: 815-819
- Evaluation of a sustained-release formulation of buprenorphine for analgesia in rats.J Am Assoc Lab Anim Sci. 2011; 50: 198-204
- Pharmacokinetic comparison of sustained-release and standard buprenorphine in mice.J Am Assoc Lab Anim Sci. 2014; 53
- Pharmacokinetic profiles of meloxicam and sustained-release buprenorphine in prairie dogs (Cynomys ludovicianus).J Am Assoc Lab Anim Sci. 2017; 56: 160-165
- Voluntary running-wheel activity, arterial blood gases, and thermal antinociception in rats after 3 buprenorphine formulations.J Am Assoc Lab Anim Sci. 2016; 55: 306-311
- Lack of absorption of a sustained-release buprenorphine formulation administered subcutaneously to athymic nude rats.J Am Assoc Lab Anim Sci. 2019; 58: 597-600
- Nalbuphine, a non-controlled opioid analgesic, and its potential use in research mice.Lab Anim. 2015; 44: 106-110
- Improving animal welfare using continuous nalbuphine infusion in a long-term rat model of sepsis.Intensive Care Med Exp. 2017; 5: 1-13
- Pharmacokinetic profiles of nalbuphine after intraperitoneal and subcutaneous administration to C57BL/6 mice.J Am Assoc Lab Anim Sci. 2017; 56: 534
- Reduction of isoflurane MAC with buprenorphine and morphine in rats.Lab Anim. 2000; 34: 252-259
- In vivo iontophoresis of fentanyl and sufentanil in rats: Pharmacokinetics and acute antinociceptive effects.Anesth Analg. 1993; 77: 61-66
- Fatal overdose after ingestion of a transdermal fentanyl patch in two non-human primates.Vet Anaesth Analg. 2012; 39: 653-656
- Case report: Intoxication in a pig (Sus scrofa domesticus) after transdermal fentanyl patch ingestion.Front Vet Sci. 2020; 7
- Chronic fentanyl or buprenorphine infusion in the mouse: similar analgesic profile but different effects on immune responses.Pain. 2004; 110: 385-392
- Analgesic efficacy of subcutaneous-oral dosage of tramadol after surgery in C57BL/6J Mice.J Am Assoc Lab Anim Sci. 2018; 57: 368-375
- Efficacy of tramadol for postoperative pain management in dogs: Systematic review and meta-analysis.Vet Anaesth Analg. 2021; 48: 283-296
- Analgesic effects of tramadol, tramadol-gabapentin, and buprenorphine in an incisional model of pain in rats (Rattus norvegicus).J Am Assoc Lab Anim Sci. 2011; 50: 192-197
- Pharmacokinetic profiles of gabapentin after oral and subcutaneous administration in black-Tailed prairie dogs (Cynomys ludovicianus).J Am Assoc Lab Anim Sci. 2020; 59: 305-309
- Pregabalin as a pain therapeutic: Beyond calcium channels.Front Cell Neurosci. 2020; 14: 83
- DEA. Drug Scheduling. Updated July 10, 2018.(Available at:) (Accessed April 20, 2022)
- Role of descending noradrenergic system and spinal α 2- adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouse.Br J Pharmacol. 2005; 144: 703-714
- Use of flavored tablets of gabapentin and carprofen to attenuate postoperative hypersensitivity in an incisional pain model in rats (Rattus norvegicus).J Am Assoc Lab Anim Sci. 2020; 59: 163-169
- Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.J Pharmacol Exp Ther. 2005; 312: 726-732
- Pregabalin antinociception and its interaction with tramadol in acute model of pain.Pharmacol Rep. 2012; 64: 576-585
- Gabapentin-induced neurologic toxicities.Pharmacotherapy. 2005; 25: 1817-1819
- Cannabidiol for pain treatment: Focus on pharmacology and mechanism of action.Int J Mol Sci. 2020; 21: 8870
- Front and hind paw differential analgesic effects of amitriptyline, gabapentin, ibuprofen, and URB937 on mechanical and cold sensitivity in cisplatin-induced neuropathy.Mol Pain. 2019; 15
- Midazolam enhances the analgesic properties of dexmedetomidine in the rat.Vet Anaesth Analg. 2010; 37: 550-556
- Morphine and clonidine synergize to ameliorate low back pain in mice.Pain Res Treat. 2012; 2012: 12
- Evaluation of analgesic interaction between morphine, dexmedetomidine and maropitant using hot-plate and tail-flick tests in rats.Vet Anaesth Analg. 2019; 46: 476-482
- Atipamezole changes the antinociceptive effects of butorphanol after medetomidine–ketamine anaesthesia in rats.Vet Anaesth Analg. 2009; 36: 591-596
- Effects of atipamezole on the analgesic activity of butorphanol in rats.J Exot Pet Med. 2017; 26: 290-293
- Atipamezole reverses ketamine-dexmedetomidine anesthesia without altering the antinociceptive effects of butorphanol and buprenorphine in female C57BL/6J mice.J Am Assoc Lab Anim Sci. 2014; 53: 675-683
- The anti-inflammatory action of maropitant in a mouse model of acute pancreatitis.J Vet Med Sci. 2018; 80: 17-0483
- Maropitant citrate.in: Papich M.G. Papich handbook of veterinary drugs. 5th edition. Elsevier, St. Louis, MO2021: 550-553
- IACUC. Analgesia (Guideline). Vertebrate Animal Research. Updated December 9, 2020.(Available at:) (Accessed January 17, 2022)
- Anesthesia, analgesia, and sedation of small mammals.in: Quesenberry K.E. Carpenter J.W. Ferrets, rabbits, and rodents. 3rd edition. WB Saunders, St. Louis, MO2012: 429-451
- Behaviour-based assessment of the duration of laparotomy-induced abdominal pain and the analgesic effects of carprofen and buprenorphine in rats.Behav Pharmacol. 2004; 15: 461-472
- Aqueous stability and oral pharmacokinetics of meloxicam and carprofen in male C57BL/6 mice.J Am Assoc Lab Anim Sci. 2013; 52: 553-559
- Effects of vasectomy surgery and meloxicam treatment on faecal corticosterone levels and behaviour in two strains of laboratory mouse.Pain. 2007; 130: 108-118
- Evaluation of analgesic efficacy of meloxicam and 2 formulations of buprenorphine after laparotomy in female Sprague–Dawley rats.J Am Assoc Lab Anim Sci. 2018; 57: 498-507
- ZooPharm Veterinary Compounding Pharmacy.(Available at:) (Accessed March 1, 2022)
- Anesthesia and analgesia in other mammals.in: Fish R.E. Brown M.J. Danneman P.J. Anesthesia and analgesia in laboratory animals. 2nd edition. Academic Press, San Francisco, CA2008: 457-480
- Evaluation of analgesic and sedative effects of continuous infusion of dexmedetomidine by measuring somatosensory- and auditory-evoked potentials in the rat.Vet Anaesth Analg. 2008; 35: 424-431
- Efficacy of sustained-release buprenorphine in an experimental laparotomy model in female mice.J Am Assoc Lab Anim Sci. 2016; 55: 66-73
- Evaluation of an improved sustained-release buprenorphine formulation for use in mice.Am J Vet Res. 2014; 75: 619-625
- Pharmacokinetics and efficacy of a long-lasting, highly concentrated buprenorphine solution in mice.J Am Assoc Lab Anim Sci. 2021; 60: 64-71
- Antinociceptive effects of sustained-release buprenorphine in a model of incisional pain in rats (Rattus norvegicus).J Am Assoc Lab Anim Sci. 2014; 53: 193-197
- Pharmacokinetic and histopathologic study of an extended-release, injectable formulation of buprenorphine in Sprague-Dawley rats.J Am Assoc Lab Anim Sci. 2021; 60: 462-469
- Pharmacokinetics and efficacy of a long-lasting, highly concentrated buprenorphine solution in rats.J Am Assoc Lab Anim Sci. 2021; 60: 667-674
- Prairie dogs.in: Quesenberry K.E. Orcutt C.J. Mans C. Ferrets, rabbits, and rodents. 4th edition. WB Saunders, St. Louis, MO2020: 334-344
- Analgesia during monkeypox virus experimental challenge studies in prairie dogs (Cynomys ludovicianus).J Am Assoc Lab Anim Sci. 2019; 58: 485-500
Article info
Identification
Copyright
Published by Elsevier Inc.